Smallpox eradication (1980)
An intensified global immunization and case-containment effort led by the World Health Organization drove smallpox from endemic status in 31 countries to zero cases worldwide. The last naturally occurring case was in Somalia in 1977, and the WHO certified global eradication in 1980.
The world stopped smallpox vaccination entirely after eradication, saving billions in future immunization costs.
Established the logical standard for disease elimination and eradication, including the surveillance and verification mechanisms that modern elimination programs adapt to individual diseases.
Smallpox is the only human disease fully eradicated; rubella elimination in Thailand is the same class of achievement at a national scale, using vaccination as the mechanism.
