Pull to refresh
Logo
Daily Brief
Following
Why Sign Up
Richard Frye

Richard Frye

Director of Autism Research, Arkansas Children's Hospital Research Institute

Appears in 1 story

Stories

FDA approves leucovorin for ultra-rare brain disorder, declines autism indication promoted by White House

Rule Changes

Leading researcher on leucovorin and autism; continues to advocate for further study

In September 2025, White House officials told parents of autistic children that a cheap, generic drug called leucovorin might improve their children's speech and behavior. Prescriptions surged 71% in the following months, pharmacies ran dry, and the Food and Drug Administration (FDA) allowed emergency imports from Canada and Spain. On March 10, 2026, the FDA approved leucovorin — but only for a genetic condition so rare that fewer than 50 cases have ever been identified worldwide, not for autism.

Updated 7 days ago