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President's Emergency Plan for AIDS Relief (PEPFAR)

President's Emergency Plan for AIDS Relief (PEPFAR)

U.S. government program

Appears in 4 stories · Last updated Nov 8, 2026

Stories

Global Fund brings back Mark Dybul to lead it through a funding squeeze

Money Moves

Effectively dismantled under the Trump administration

The Global Fund to Fight AIDS, Tuberculosis and Malaria named Mark Dybul as its next executive director on 28 October 2026, returning him to a job he held from 2013 to 2017. He starts a four-year term in early 2027, replacing Peter Sands, who has led the organization since 2018.

Updated 3 days ago

A twice-yearly HIV shot arrives as funding to deliver it shrinks

New Capabilities

Major funder; Trump administration has announced permanent shutdown by early 2027

On Nov. 2, the U.S. Food and Drug Administration gave tentative approval to a generic version of lenacapavir made by India's Dr. Reddy's Laboratories. The twice-yearly shot is expected to sell for about $40 per person per year in 120 low- and middle-income countries. It cannot be sold in the U.S.

Updated Nov 3

Global HIV infections and AIDS deaths fall to three-decade lows

New Capabilities

As of August 2026: Largest single HIV funder

In 1995, HIV infected about 3 million people in a single year. In 2022 that number fell to 1.3 million, the fewest since the late 1980s.

Updated Aug 5

Trump freezes aid, threatens South Africa over land law

Force in Play

As of May 2026: Funding frozen to South Africa

President Trump cut all US aid to South Africa on February 7, 2025—$440 million annually, most for HIV treatment—over a land law allowing seizure without compensation. He called it discrimination against white farmers.

Updated May 19