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Spanish National Cancer Research Centre (CNIO)

Spanish National Cancer Research Centre (CNIO)

Research Institution

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The race to drug KRAS in pancreatic cancer

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PNAS paper retracted April 2026 for undisclosed competing interests; triple-therapy research ongoing with paper resubmitted for independent peer review

On May 31, Revolution Medicines presented the full Phase 3 RASolute 302 dataset at the ASCO plenary in Chicago, simultaneously published in the New England Journal of Medicine. Daraxonrasib cut the risk of death by 60%. The drug produced a 33.2% objective response rate versus 11.8% on chemotherapy and nearly halved the rate at which patients' pain worsened.

Updated 7 days ago