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Baylor College of Medicine

Baylor College of Medicine

Academic Medical Center

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Stories

Scientists achieve first sustained laboratory growth of human norovirus

New Capabilities

Institution where breakthrough was achieved

For nearly six decades, human norovirus has defied laboratory cultivation—making it impossible to develop effective vaccines against a pathogen that sickens 700 million people annually. Researchers at Baylor College of Medicine have now broken that barrier. By blocking chemokine signaling with a drug called TAK-779, the team achieved 10 to 15 consecutive rounds of viral replication in lab-grown human intestinal tissue, enabling production of stable virus stocks for the first time.

Updated Feb 5