Sasol coal-to-liquids scale-up (1955)
South Africa's Sasol turned Fischer-Tropsch chemistry, known since the 1920s, into a full industry making liquid fuel from coal. It took massive capital and decades of engineering to move from lab reactions to plants.
Sasol produced synthetic fuel at commercial scale, though only with heavy state backing.
It proved carbon-conversion chemistry can industrialize, but also that scale-up is slow and cost-sensitive.
Like the plastic-to-hydrogen work, the underlying chemistry was sound in the lab. The hard part, then and now, is cheap, continuous scale.
