TRUTH study investigators (Amsterdam UMC)

New Capabilities

As of October 2026: Reported phase 2 results in Nature Metabolism, October 2026

Eight of 17 patients whose fatty liver disease had progressed to scarring saw their fibrosis improve after 21 weeks of intermittent treatment with two drugs. One of 14 on placebo did. The randomized, placebo-controlled result, published in Nature Metabolism, is the first controlled evidence that clearing senescent cells can reverse liver fibrosis in people.

Updated Oct 7