Matthew Greenblatt

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Scientists identify the stem cell that builds tendons and ligaments

As of September 2026: Co-senior author of the Cell study

Researchers have isolated the stem cell that builds tendons and ligaments in both mice and humans, for the first time. The cell, identified by a specific set of surface markers, self-renews and produces every other cell type in these tissues.

Updated Sep 8

Notable Quotes

We looked in the kneecap ligament; we looked at the Achilles tendon; and everywhere we looked, we found this cell. So, we think this is the universal stem cell for tendons and ligaments throughout the body.

from Scientists identify the stem cell that builds tendons and ligaments · Updated Sep 8

Though spinal stenosis is a complex condition, this really showed us that these cells are contributing to the pathology.

from Scientists identify the stem cell that builds tendons and ligaments · Updated Sep 8