Chief Executive Officer, Celldex Therapeutics
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Last updated Sep 22, 2026
As of September 2026: Leading company through its pivot to immunology
Celldex's experimental antibody barzolvolimab beat placebo in two Phase 3 trials for chronic spontaneous urticaria, the condition behind recurring hives and severe itching. Roughly 42% to 46% of treated patients were completely symptom-free at 12 weeks, versus about 10% on placebo. The drug works by depleting the mast cells that drive the disease—a mechanism no approved CSU therapy uses.
Updated Sep 22
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