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Howard Hughes Medical Institute

Howard Hughes Medical Institute

Nonprofit medical research organization

Appears in 4 stories · Last updated Nov 1, 2026

Stories

First whole-body cell atlas maps an adult vertebrate

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Funds Reddien's lab and publicized the atlas

Mapping every cell in an adult vertebrate has been out of reach for a simple reason: most vertebrates are too big. A 12-millimeter transparent fish called Danionella cerebrum removed that obstacle. Researchers catalogued 607,370 cells from 12 body regions and mapped where the major cell types sit.

Updated Nov 1

Mitochondria atlas across tree of life reveals parasite drug targets

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Funded the project through its Emerging Pathogens Initiative

Scientists have mapped the full set of mitochondrial proteins in six organisms: five parasites and one plant. Combined with existing human and yeast inventories, the catalog covers 8,619 proteins in 3,199 families, including 33 families found in parasites but not in people.

Updated Oct 21

Bacterial antiviral enzyme builds DNA repeats like telomerase

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Funds Samuel Sternberg's lab

Bacteria fight viruses with an enzyme that writes repetitive DNA from an RNA template. The system, called DRT10, works much like telomerase, the enzyme that protects chromosome ends in humans and most other eukaryotes.

Updated Oct 12

Nobel Prize in medicine honors optogenetics pioneers

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As of October 2026: Funds Deisseroth's lab

The 2026 Nobel Prize in Physiology or Medicine went to three scientists who built a way to switch individual nerve cells on and off with light. Karl Deisseroth, Peter Hegemann and Georg Nagel share the 12 million Swedish kronor prize for optogenetics.

Updated Oct 8