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Harvard Stem Cell Institute

Harvard Stem Cell Institute

Academic Research Institute

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Stories

MSI2 protective variant against blood cancer discovered

New Capabilities

Co-led the research

For decades, cancer genetics meant finding mutations that raise risk. Now scientists have found one that lowers it. A variant in the MSI2 gene reduces the risk of blood cancers by up to 30% in people who carry two copiesโ€”the first protective genetic variant identified against myeloid malignancies.

Updated Jan 28