Cholesterol Treatment Trialists' Collaboration

New Capabilities

As of May 2026: Conducted the meta-analysis

More than 200 million people worldwide take statins for heart health. For decades, package inserts have warned about 66 potential side effects, from memory loss to depression to muscle pain. The February 2026 Lancet analysis of 23 major clinical trials with nearly 155,000 participants found 62 of those warnings unsupported by evidence, with symptoms appearing equally in statin and placebo groups.

Updated May 29