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Cell

Cell

Peer-reviewed scientific journal

Appears in 10 stories · Last updated Nov 9, 2026

Stories

CRISPR map of the MYC locus reveals a druggable RNA element

New Capabilities

Published the MYC locus study

For decades, the MYC oncogene has been considered hard to drug: it makes a transcription factor, not an enzyme with a ready pocket. A new Cell paper maps every base pair in a 10-kilobase stretch of the locus and finds that most of what matters for cancer cell growth is noncoding.

Updated 3 days ago

Algae inside a marine worm move on the host's actin

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Published the study

A single-celled alga can move hundreds of micrometers through the body of a marine worm, even while squeezed inside host-cell tubes about 200 nanometers wide. The alga, Amphidinium, still has its flagella. But when researchers tracked it inside live Waminoa worms, they found the host's actin machinery was doing the moving.

Updated Nov 2

A bioavailable GPX4 inhibitor induces ferroptosis in mice and suppresses metastasis

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Published the KY0418 study

For more than a decade, ferroptosis researchers could trigger the iron-dependent cell death in a dish but not reliably in an animal. The compounds that block GPX4, the enzyme that keeps lipid peroxides in check, tended to fall apart in blood or fail to reach tissue. A study published in Cell on 21 October 2026 describes KY0418, a covalent GPX4 inhibitor designed to survive in plasma and distribute through the body after oral dosing in mice.

Updated Nov 2

Retrotransposons write CAR genes into T cells inside living mice

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Published the study online on 21 October 2026

CAR-T therapy starts with a patient's T cells being removed, engineered in a lab and reinfused. A paper in Cell reports skipping the removal: engineered retrotransposons, delivered as RNA in lipid nanoparticles, inserted a receptor gene into T cells inside living mice.

Updated Nov 1

Orphan rice gene confers drought tolerance across five crop species

New Capabilities

Publisher of the ROAD1 paper

Breeders have spent decades looking for drought-tolerance genes that do not cost yield in normal years. Rice lines carrying a newly described gene, ROAD1, yielded up to 34.75% more grain under field drought, with no growth penalty in normal conditions.

Updated Oct 26

Structural variant map of 467,152 UK Biobank genomes ties rare DNA rearrangements to disease

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Publisher of the study, available online October 15, 2026

AstraZeneca's genomics team scanned 467,152 UK Biobank genomes for structural variants, the large DNA rearrangements most studies skip, and tied them to disease and blood proteins. It is the largest phenome-wide map of structural variants published so far.

Updated Oct 17

In-cell imaging reveals how bacteria coordinate protein production and transport

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As of September 2026: Published both papers online September 25, 2026

For decades, structural biologists had to purify molecules before they could image them. The ribosome's structure was solved from isolated particles, frozen in test tubes. Two papers in Cell now show the same machinery at work inside intact bacterial cells, exposing coordination that was only theorized before.

Updated Sep 26

IL-21 mimic converts transient KRAS inhibitor responses into durable remissions in pancreatic cancer

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As of September 2026: Published the study

Pancreatic cancer ignores nearly every approved immunotherapy, and the new KRAS inhibitors shrink tumors only until resistance emerges. A study published online this week in Cell pairs those inhibitors with a designer mimic of the immune signal IL-21 — and in mice, the combination cleared pancreatic tumors and kept them clear for months.

Updated Sep 24

Geothermal amoeba sets new upper temperature limit for eukaryotes

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As of September 2026: Published the study

A single-celled organism found in a California hot spring can eat and reproduce at 63°C (145°F), a temperature that kills every other known complex life form. The amoeba, named Incendiamoeba cascadensis, breaks the 60°C record that had stood for decades.

Updated Sep 23

Scientists identify the stem cell that builds tendons and ligaments

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As of September 2026: Publisher of the study

Researchers have isolated the stem cell that builds tendons and ligaments in both mice and humans, for the first time. The cell, identified by a specific set of surface markers, self-renews and produces every other cell type in these tissues.

Updated Sep 8